After two months and three sessions of Plinest, a polynucleotide skin booster, this writer has ditched her cushion foundation and hasn’t looked back
“Wait, what? You don’t have any make-up on?” My colleagues’ tones were more incredulous than dismissive. But it was true. My skin looked plump, with a visibly healthy barrier and dullness eradicated; all I had on my base for the day was moisturiser, sunscreen, and a bit of blush on my cheeks to add some life. There was absolutely no need for my usual cushion foundation, and I attributed all credit to Plinest, for sure.
What’s that, you ask? Plinest is a pioneer in polynucleotide (PN) technology, backed by decades of clinical research (yes, that means that it’s been around long before PDRN came onto the scene). In short, it champions long-term skin health over quick fixes, working toward a natural, lasting glow–like a gift that keeps on giving, rather than an overnight transformation that needs constant topping-up to stick around.
I’d always wanted to try skin boosters but had never gone under the needle on my face. One of the most talked-about treatments I’d heard of was PDRN, better known to most as Rejuran, but the downtime remained the biggest hurdle I could never get over. Multiple injection points and the raised bumps that follow triggered a mild tryphophobia response in me, and frankly, I didn’t think it was worth the trade-off for the clear, smooth, and glowing skin every content creator seemed to be raving about on social media.
So then, when offered Plinest trial sessions administered via cannula, a single entry point instead of multiple sharp-needle punctures (and no trypophobia-inducing “blebs” afterward), the only hurdle left was getting the appointment in my calendar. Off I went to meet Dr Vivian Yong, an aesthetic doctor at IDS Aesthetics.
I’ve had three sessions of Plinest spaced roughly four weeks apart, and exactly two months on from my first session, the effects are still holding strong: my skin still looks brighter, plumper, and bouncier than it had ever been. I was told results typically last between six and 12 months, which is a solid return on investment if you ask me.
The three kids on the block

First in the line-up, there’s Plinest, lovingly dubbed the multi-tasking all-rounder. This original formulation stimulates collagen production and boost fibroblast activity, improving elasticity and hydration while restoring overall radiance. It’s the go-to for comprehensive anti-ageing across the face, neck, and décolletage.

Then there’s Plinest Fast, which promises to rescue the eye area. Formulated for thinner, more delicate skin like the periocular area, it targets fine lines, dark circles, and visible fatigue with a lighter touch and quicker results that’s observable, making this a hot favourite before or after eyelid procedures.

If you’re looking for a glow and hydration power combo, Plinest Newest would be the one to pick. Combining polynucleotides with hyaluronic acid and antioxidants, this one intensely hydrates, firms, and refines texture while plumping and boosting radiance, which sounds to us like the ideal choice for those chasing anti-ageing results and an instant glow.
The original formulated Plinest is priced at S$800 (S$872 with GST) per syringe at IDS Aesthetics, with Plinest Fast and Newest priced separately.
Header photo by Simon Ebele